Risk of Breast Cancer

Risk of Breast Cancer -Breast cancer is not a transmissible or infectious disease.  Unlike some cancers that have infection-related causes, such as human papillomavirus (HPV) infection and cervical cancer, there are no known viral or bacterial infections linked to the development of breast cancer.

Approximately half of breast cancers disease develop in women who have no identifiable breast cancer risk factor other than gender (female) and age (over 40 years).  Certain factors increase the risk of breast cancer including increasing age, obesity, harmful use of alcohol, family history of breast cancer, history of radiation exposure, reproductive history (such as age that menstrual periods began and age at first pregnancy), tobacco use and postmenopausal hormone therapy.

Behavioural choices and related interventions that reduce the risk of breast cancer include:

  • prolonged breastfeeding;
  • regular physical activity;
  • weight control;
  • avoidance of harmful use of alcohol;
  • avoidance of exposure to tobacco smoke;
  • avoidance of prolonged use of hormones; and  
  • avoidance of excessive radiation exposure.

Certain inherited “high penetrance” gene mutations greatly increase breast cancer risk, the most dominant being mutations in the genes BRCA1, BRCA2 and PALB-2.  Women found to have mutations in these major genes could consider risk reduction strategies such as surgical removal of both breasts. Consideration of such a highly invasive approach only concerns a very limited number of women, should be carefully evaluated considering all alternatives and should not be rushed.

WHO Finding

The objective of the WHO Global Breast Cancer Initiative (GBCI) is to reduce global breast cancer mortality by 2.5% per year. Thereby averting 2.5 million breast cancer deaths globally between 2020 and 2040. Reducing global breast cancer mortality by 2.5% per year would avert 25% of breast cancer deaths by 2030 and 40% by 2040 among women under 70 years of age. The three pillars toward achieving these objectives are: health promotion for early detection; timely diagnosis; and comprehensive breast cancer management.

Source: https://www.who.int/news-room/fact-sheets/detail/breast-cancer

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